Oxycodone Interaction

What other drugs affect Oxycodone?

Oxycodone is given to relieve pain. But your medication will only work best of you are open with your doctor about your current medication, existing ailments and your lifestyle issues. There are several drugs that clash with Oxycodone and it is dangerous to take them all at the same time. Some of these include nalbuphine, buprenorphine, utorphanol, and pentazocine which are not conducive to narcotic painkillers. If you are taking them then special dosage or tests are needed during the entire treatment. Your regular vitamins or over the counter drugs may also clash and therefore you need to consult your doctor at all times before taking them.

Alcohol intake is a total no-no during Oxycodone medication. This drug has minor side-effects but combined with alcohol they could become dangerous. Drowsiness and breathlessness and even temporary amnesia could occur.

Along with alcohol you also need to avoid tranquillizers, sleeping pills, muscle relaxants and other opioids. These can cause extreme lethargy and sleepiness, shallow breathing and lowering down of heart rate. Consult your doctor immediately if you feel any of these.


What should I avoid while taking Oxycodone?

Oxycodone by itself has numbing qualities as it contains narcotics. If accidentally or otherwise combined with alcohol or any other narcotic then the results could be fatal. Make sure you drive slow and safe to balance your low alert system during medication.

Alcohol alert

There should zero consumption of alcohol while you are on Oxycodone medication. Not should you avoid drinking, but you should also avoid taking other medications which contain alcohol in them.


Explanation of drug interactions

If you are on antidepressants or planning to take some then you need to consult your doctor for possible effects of Oxycodone clash. Oxycodone and antidepressant combo can have serious side-effects like amnesia, confusion and drowsiness. If the intake of both is not monitored and the Oxycodone dosage is not adjusted or changed, results could be fatal.

The same could be said of the Oxycodone and antipsychotic medication combo. Be open with your doctor not just for best pain relief, but for better all round health development.

If you are on Oxycodone then any medication with barbiturate will have dangerous effects. You will feel nauseous, confused, be forgetful, have difficulty in breathing and feel listless.

Benzodiazepine based medication also needs to be avoided. Benzodiazepine and Oxycodone do not go well together. From breathlessness to mental numbness the effects could oscillate from dangerous to fatal. Talk to your doctor if you have accidentally mixed the two and are feeling the negative effects.

No other narcotic should be combined or taken with Oxycodone. They should be avoided along with alcohol. No tranquillizers, sleeping pills or relaxants should be taken either. All these medications and drugs have soporific qualities and if combined can have fatal consequences.

It is if utmost importance to consult your doctor and pharmacist of all possible side-effects if there is any chance of such combinations. There are many drugs out there which clash with Oxycodone medications. Ask your doctor for more information on the same.


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More Oxycodone pain management information:

  • Oxycodone Interactions by eMedTV.com - find out how the medicine interaction with other medications.
  • Drugs.com guide list 27 major, 641 moderate and 3 minor drug interactions with Oxycodone.
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